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Hamdoun, Amro

Assistant Professor of Biology

Degrees:

• B.S., University of California, Davis
• Ph.D., University of California, Davis

Research Interests:

• Structure, function and dynamics of the plasma membrane during embryonic development.
• Live cell and and super resolution imaging of embryos.
• ABC transporters in development and environmental toxicology.
• Emerging marine pollutants and methods for predicting pollutant persistence.

Courses Recently Taught:

• ESYS101: Environmental Biology
• SIO 189: Pollution, Environmnt & Health
• SIO 289: Pollution, Environmnt & Health
• SIO 297: Marine Biology Seminar
• SIO296: Special Topics/Marine Biology

Honors and Awards:

• Poptech Science and Public Leadership Fellow 2010
• NIH NRSA Postdoctoral Fellow, Stanford University 2004-2008
• NIH K99 Career Development Award Recipient 2008

Mentoring:

• Espinosa, Jose (Undergrad; 2011-)
• Hill, Rose (Undergrad; 2011-)
• Gokirmak, Tufan (Post Doc; 2010-)
• Whalen, Kristen (Post Doc; 2010-2012)
• Campanale, Joseph (Graduate; 2009-)
• Shipp, Lauren (Graduate; 2009-)
• , (Graduate; -)

• Shipp, L.E. and Hamdoun, A. (2012) ATP Binding Cassette transporter expression and localization in sea urchin development. Developmental dynamics. 241:1111-1124.

• Campanale, J. P. and Hamdoun, A. (2012) Programmed reduction of ABC transporter activity in sea urchin germ line progenitors. Development. 139: 783-792.

• Patel, S., Ramkrishnan, L., Rahman, T., Hamdoun, A., Marchant, J.S., Taylor, C.W., and Brailoiu, E. (2011). The endolysosomal system as an NAADP -sensitive acidic Ca (2+) store: role for the two-pore channels. Cell Calcium 50: 157-167.

• Epel, D., Stevenson, C.N., MacManus-Spencer, L.A., Luckenbach, T., Hamdoun A. and Smital, T. (2007) Efflux transporters: newly appreciated roles in protection against pollutants. Environmental Science and Technology. In press.

• Hamdoun, A. and Epel, D. Embryo stability and vulnerability in an always changing world. (2007). PNAS 104, 1745-1750.

• The Sea Urchin Genome Consortium. The Genome of the Sea Urchin, Strongylocentrotus purpuratus. Hamdoun, A., Defense Gene Group Leader. (2006) Science. 314: 941-952.

• Goldstone, J. V*, Hamdoun, A.* (*equal contributions), B.J. Cole, M.H. Ashby, M. Scally, M.E. Hahn, M. Dean, Epel, D. and J.J. Stegeman. (2006) The chemical defensome: Environmental sensing and response genes in the Strongylocentrotus purpuratus genome. Developmental Biology, 300(1), 366-384.

• Roepke, T. A., Hamdoun, A. and G.N. Cherr. (2006) Increased drug transport activity is associated with the translocation of a MDR-related protein following induction of sea star oocyte maturation. Development, Growth and Differentiation, 48(9)559-573.

• Epel, D., Cole, B., Hamdoun A. and Vega, R.L. (2006). The sea urchin embryo as a model for studying efflux transporters: genomics, roles and energy cost of this protection system. Marine Environmental Research, 62, S1-S4.

• Hamdoun, A, Cherr, G.N., Roepke, T.A., and D. Epel (2004). Post-Translational Activation of MRP and P-gp Mediated Efflux Transport Activity at Fertilization in Sea Urchin Embryos (Strongylocentrotus purpuratus). Developmental Biology, 276, 452-462.

• Smital, T., Luckenbach, T., Sauerborn, R., Hamdoun, A., Vega, R. and Epel, D. (2004) Emerging contaminants - PPCPs, pesticides and microbial degradation products as inhibitors of the multixenobiotic defense in aquatic organisms. Mutation Research, 552, 101-117.

• Hamdoun, A., Cheney D. P. and Cherr, G.N. (2003). Phenotypic plasticity of HSP and HSP70 gene expression in the Pacific oyster (Crassostrea gigas): Implications for resting thermal limits and induction of thermal tolerance. Biological Bulletin, 205, 160-169.

• Hamdoun, A., Griffin, F.J. and Cherr, G.N. (2002). Tolerance to biodegraded crude oil in marine invertebrate embryos and larvae is associated with expression of a multixenbiotic resistance transporter. Aquatic Toxicology, 61, 127-140.