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TAYLOR, STEVEN

Research Associate

Degrees:

• B.S., University of Queensland, Brisbane, Australia
• Ph.D., University of Queensland, Brisbane, Australia

Research Interests:

• Mass Spectrometry of Biomolecules, Proteomics and Peptidomics
• Polypeptides with unusual post-translational modifications from marine invertebrates, structure, function, and application
• Biochemical mediators of innate immunity in invertebrates: Cytotoxicity and antimicrobial activity
• Marine bioinorganic chemistry of metal binding proteins from marine invertebrates

Honors and Awards:

• Commonwealth Postgraduate Research Award (CPRA) February 1988 - December 1989.
• Australian Postgraduate Research Award (APRA) January 1990 - February 1992.
• Alexander von Humboldt Research Fellowship October 1995 -March 1997.

Mentoring:

• Tincu, J. Andrew (Graduate; 1999-2003)

2010. A primary colonic crypt model enriched in enteroendocrine cells facilitates a peptidomic survey of regulated hormone secretion. Nikoulina SE, Andon NL, McCowen KM, Hendricks MD, Lowe C, Taylor SW. Mol Cell Proteomics 9:728-741.

2008. A sulfated, phosphorylated 7 kDa secreted peptide characterized by direct analysis of cell culture media. Taylor SW, Sun C, Hsieh A, Andon NL, Ghosh SS. J Proteome Res.7:795-802.

2006. Efficient high-throughput discovery of large peptidic hormones and biomarkers. Taylor SW, Andon NL, Bilakovics JM, Lowe C, Hanley MR, Pittner R, Ghosh SS. J Proteome Res. 5:1776-84.

2004. Antimicrobial peptides from marine invertebrates. Tincu JA, Taylor SW. Antimicrob Agents Chemother. 48:3645-54.

2004. Identification of Protein Associations in Organelles, Using Mass Spectrometry-Based Proteomics. Warnock DE, Fahy E, Taylor SW Mass Spectrometry Reviews 23: 259-280.

2003. Characterization of the human heart mitochondrial proteome. Taylor SW, Fahy E, Zhang B, Glenn GM, Warnock DE, Wiley S, Murphy AN, Gaucher SP, Capaldi RA, Gibson BW, Ghosh SS. Nat Biotechnol. 21:281-6.

2003. Fragmentation of tunichrome Sp-1 is dominated by an unusual gas-phase intramolecular rearrangement. Taylor SW, Kassel DB, Tincu JA, Craig AG. J Mass Spectrom. 38:1105-9.

2002. Chemoenzymatic synthesis of peptidyl 3,4-dihydroxyphenylalanine for structure-activity relationships in marine invertebrate polypeptides. Taylor SW. Anal Biochem. 302:70-4.

1996. Ferric ion complexes of a DOPA-containing adhesive protein from Mytilus edulis. Taylor SW, Chase DB, Emptage MH, Nelson MJ, Waite JH Inorganic Chemistry: 35:7572-7577.